SC INBRE announces $695,000 in funding awarded to FY2022 Project Program Grant Recipients

FOR IMMEDIATE RELEASE
January 22, 2023


Columbia, SC — South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE), a statewide $18.9 million, five-year renewable grant program funded by The National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS), is pleased to announce our FY2022-2023 Project Program grants recipients.

The Bioinformatics Pilot Project Program (BIPP) program is designed to stimulate the application of genomics and bioinformatics methods by supporting research and student training through the SC INBRE and South Carolina Clinical & Translational Research (SCTR) networks. BIPP proposals focus on Biomedical Science and fit within the broad scientific focus areas of SC INBRE: Biochemistry/Cell and Molecular Biology, Bioinformatics, Bio/Biomedical Engineering and Regenerative Medicine, and Neuroscience. The program supports independent, faculty-driven research and provides research training to students and/or postdoctoral fellows in Bioinformatics. Each project awards up to $10,000 for one year.

The 2022 BIPP Program recipients are:

Linnea Freeman

Furman University
Biology

Fecal microbiome evaluation in a mouse model of autism

Chakia McClendon

Columbia College
Biology

Kinome Expression Profiling of Airway Cells Exposed to Electronic and Conventional Cigarettes

Kandy Velazquez

University of South Carolina School of Medicine Columbia
Pathology, Microbiology & Immunology


Development of pain biomarkers to assess analgesia and predict pain in pre-clinical models of cancer pain

The Developmental Research Project Program (DRP) program was designed to foster faculty research programs at SC INBRE network institutions. DRP projects must focus on Biomedical Science and fit within the broad scientific focus areas of SC INBRE: Biochemistry/Cell and Molecular Biology, Bioinformatics, Bio/Biomedical Engineering and Regenerative Medicine, and Neuroscience. The program awards support independent research programs and, in the process, provide research training to students and/or postdoctoral fellows in the Biomedical Sciences. Each project awards up to $50,000 for one year, renewable for a second year upon favorable review of the progress report by SC INBRE’ s External Advisory Committee.

The 2022 DRP Program recipients are:

Timothy Barker
NEW

College of Charleston
Chemistry/Biochemistry


Synthesis and Biological Evaluation of 5-HT antagonists

Meghan Breen
2nd YEAR

Furman University
Chemistry


Effects of Pdr1 phosphosites on azole resistance in Candida glabrata

Heather Dunn
NEW

Clemson University
Bio
engineering


Novel Investigations of Breast Cancer Racial Disparities based on Deep Learning and Bioinformatics Analysis

Mindy Engevik
NEW

Medical University of South Carolina
Regenerative Medicine & Cell Biology


Microbial suppression of intestinal inflammation and oxidative stress

Timea Fernandez
NEW

Winthrop University
Chemistry


Using Antibiotic-Binding Nucleic Acid Aptamers as Trojan-Horse Delivery Vehicles in the Fight Against Drug-Resistant Bacteria

Jordon Gilmore
2nd YEAR

Clemson University
Bioengineering


Point-of-Care Colorimetric Biosensor for Detection of Pseudomonas aeruginosa Signaling Molecule 3OC12HSL in Wound Exudate from Negative Pressure Wound Therapy

Veronica Flores
NEW

Furman University
Psychology


The impact of innocuous taste experience on long-term taste-learning and memory persistence

Meredith Frazier
NEW

College of Charleston
Chemistry/Biochemistry


Structural and Functional Characterization of Viral Ribonucleases

Chiara Gamberi
NEW

Coastal Carolina University Biology


Modeling renal cyst mechanisms in the fruit fly Drosophila melanogaster

Anita Nag
3rd YEAR

USC Upstate
Chemistry


Connecting host shutoff by SARS coronavirus nsp1 to pre-mRNA processing and mRNA trafficking

Subramanya Pandruvada
2nd YEAR

Medical University of South Carolina
Oral Health Sciences


Modeling macrophage response in periodontal infections

Daniel Stovall
2nd YEAR

Winthrop University
Biology


Role and Regulation of Ring1 and YY1 binding protein in Glioblastoma Multiforme

Kristy Welshhans
NEW

University of South Carolina
Biomedical Sciences


Molecular and cellular basis of altered neural development in Down syndrome

In addition to the two grants listed above which are focused on supporting faculty research, SC INBRE also offers a student-focused opportunity entitled Student-Initiated Research Project Program (SIRP). The SIRP program is designed to enrich the academic experience of students and to better prepare the future generation of researchers, investigators, and entrepreneurs throughout the SC INBRE network. SIRP recipients apply bioinformatics tools to biomedical research questions that fit within the broad scientific focus areas of SC INBRE: Biochemistry/Cell and Molecular Biology, Bioinformatics, Bio/Biomedical Engineering and Regenerative Medicine, and Neuroscience. SIRP awards support bioinformatics training for undergraduate or graduate students. Each project awards up to $3,000 for one year.

The 2022 SIRP Program recipients are:

Patrice Cunningham, graduate student

Dr. Kandy Velazquez, mentor

USC School of Medicine Columbia
Pathology, Microbiology & Immunology

Identification of quercetin targets in skeletal muscle as a novel treatment of cancer cachexia

Ethan Older, graduate student

Dr. Jie Li, mentor

University of South Carolina
Chemistry and Biochemistry

Discovery of selective inhibitors of pro-inflammatory sulfonolipids produced by human gut microbiota

Mark Pitman, graduate student

Dr. Jessica Larsen, mentor

Clemson University
Chemical and Biomolecular Engineering

Applying a Citrate Biomaterial to Reduce Ferroptosis in Spinal Cord Injury

Alia Sadek, medical student

Dr. Jennifer Grier, mentor

USC School of Medicine Greenville
Biomedical Sciences

Identifying Mechanisms of Resistance in Novel Acinetobacter baumannii Necrotizing Fasciitis Isolates

Mihyun Waugh, graduate student

Dr. Melissa Moss, mentor

University of South Carolina
Biomedical Engineering

Blood Cytokine Levels and Healthcare Data as Predictors of Mesh Exposure After Pelvic Organ Prolapse Surgery

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ABOUT SC INBRE
SC INBRE is a statewide, multi-million dollar, five-year renewable grant program funded by The National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) to support biomedical research and infrastructure in South Carolina. Currently in Cycle IV (2020-2025), SC INBRE’s network includes 14 member and 4 outreach institutions of higher learning. SC INBRE offers biomedical research faculty and students career development, mentorship, and funding, as well as oversees a summer Research Experiences for Teachers (RET) program which gives middle school and high school STEM teachers the opportunity to do research with a faculty mentor at an institution near their location.

MEDIA CONTACT
Cyndy Buckhaults
Communications Manager
SC INBRE Program
http://scinbre.org
cyndy.buckhaults@uscmed.sc.edu
(803) 546-4569