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NOW Registering and accepting abstracts: 17th annual SC INBRE Science Symposium – Sat, Feb 21, USC Columbia (Abstracts due Jan 23!!!)
For those seeking Bioinformatics Services or information our NEW Data Science Core, please contact Dr. Edie Goldsmith (Email).
SC INBRE Supported and Recommended Cores
SC INBRE’s NEW Data Science Core (DSC) aims to increase the data science biomedical workforce in South Carolina by developing data science proficiency among faculty and students participating in biomedical research. This will occur through education, professional development (training), and resource and infrastructure enhancement to cultivate a data science driven research environment promoting interdisciplinary collaboration to address biomedical and health-related research questions. To this end, the Data Science Core is designed to support all data science and bioinformatics research activities within the SC INBRE network to advance cutting-edge biomedical research.
The Core is co-directed by Drs. Banky Olatosi and Jiajia Zhang at the University of South Carolina Arnold School of Public Health.
For more info, visit our WEBPAGE to learn more about the Core, upcoming seminars and to request a consultation.
The Data Science Core is supported by SC INBRE (NIGMS GM103499).
The mission of the core is to provide MUSC and other regional investigators with expertise, instrumentation, training, and services for a range of molecular technologies. The core currently offers Bioanalyzer service for qualitative analysis of eukaryotic total RNA and quantitative analysis of DNA libraries. Several instruments are available to users, including qPCR, PCR, NanoDrop, microplate reader, and Qubit fluorometers. The core also offers bioinformatic analysis in support of bulk RNA-seq data analysis and other miscellaneous applications. For RNA-seq projects, the core can access raw data from providers, run data analysis pipelines, securely store the data until publication, and assist users with submission of project data to public archives.
For more info, contact:
Dr. Jeremy “Jamie” Barth
Medical University of South Carolina
(843) 792-9984 | Email
The Molecular Analytics Core is supported in part by NIGMS GM103499, MUSC’s Office of the Vice President for Research, and the MUSC Department of Regenerative Medicine and Cell Biology.
Located on the VA campus of the USC School of Medicine Columbia, the IRF houses several major pieces of state-of-the-art biotechnological equipment that provide investigation ranging from single cell and molecular level analysis to whole animal imaging. Additionally, the IRF maintains a full range of ancillary equipment available for sample preparation, image enhancement, and data analysis.
For more info, contact:
Dr. Austin Worden
University of South Carolina School of Medicine Columbia
(803) 216-3823 | Email
Discounted usage of the USC Instrumentation Research Facility (IRF) for PUIs.
The IRF will give a discount to researchers from SC INBRE’s PUIs and Outreach Institutions. This discount allows eligible external researchers to access all IRF equipment and services at internal pricing, ensuring greater affordability and support for their research needs. Contact Dr. Worden for more info.
Additional Cores in South Carolina
Functional Genomics Core, located at USC College of Pharmacy, Columbia, SC
The Functional Genomics Core Facility offers state-of-the-art resources and solutions for conducting genomics, transcriptomics, epigenomics and functional genomics projects.
FGC works with researchers to determine project goals and design custom solutions. FGC assists at all stages of the projects, from support in grant development to generation of publication-quality data.
For more info, contact:
Dr. Michael “Misha” Shtutman
Director
Email
NMR Facility, located at Claflin University, Orangeburg, SC
The Claflin Molecular Science Research Center has been designated a Research Core Facility Core Research Facility for the state by SCRA because of specialized analytical equipment in the Molecular Science Research Center. Claflin has the second largest NMR in the state of South Carolina, 700 MHz Bruker NMR. Claflin also has a 300 MHz NMR and additional high-end equipment.
For more info, contact:
Mr. Stephon Void
Claflin University
(803) 535-5293 | Email
Visit NMR Facility under Molecular Sciences Research Laboratory on Claflin’s Facilities web page
Clemson University Genomics and Bioinformatics Facility, Clemson, SC
The Clemson University Genomics and Bioinformatics Facility (CUGBF) helps investigators use the latest genomics technologies in their research. The heart of our facility is Illumina’s Nextseq 2000 NGS platform, which offers high throughput sequencing used in many applications such as whole-genome, transcriptome, and targeted resequencing. CUGBF offers services to support the use of the Nextseq 2000 from experimental design through bioinformatic deliverables. We also have a 10x Genomics Chromium X and Illumina Single Cell equipment for single cell sequencing. In addition to offering a full-service genomics lab and bioinformatics team, we pride ourselves in offering training to students to work alongside our staff members to learn genomic and bioinformatic techniques. Outside of the lab, we offer training and informational workshops to Clemson’s diverse scientific community.
For more info, contact:
Dr. Rooksie Noorai
Assistant Director of Bioinformatics
Email
Clemson University Institute for Human Genetics: Genomics Core and Statistical and Bioinformatics Core, Clemson University, Clemson, SC, and Greenwood Genetic Center, Greenwood, SC
The Clemson University Institute for Human Genetics is housed in Self Regional Hall, a state-of-the-art research and educational facility located in Greenwood, South Carolina. Research in the center focuses on genomic, computational and comparative genetic approaches to gain insights in genetic and environmental risk factors for human diseases.
The Institute promotes a collaborative interdisciplinary environment that involves faculty in Self Regional Hall and affiliated Institute members from the Department of Biological Sciences, the Department of Genetics and Biochemistry, and the School for Mathematics and Statistics on the main Clemson University campus. The Institute for Human Genetics actively engages regional, national and international partnerships and provides excellent opportunities for graduate students and postdoctoral research.
Genomics Core
The Genomics Core provides cutting-edge, end-to-end support for modern genomics research, offering state-of-the-art infrastructure for high-throughput sequencing and molecular biology workflows. Our expert staff work closely with investigators from experimental design through sequencing, ensuring high-quality results across a broad range of applications, including whole-genome sequencing, RNA-seq, single-cell sequencing (10x Genomics, Parse, and Illumina), and more. Equipped with advanced platforms such as the Illumina NovaSeq X+, PacBio Revio, ONT PromethION P2 Integrated, and 10x Genomics Chromium iX, the Genomics Core is a collaborative partner ready to support the evolving needs of cutting-edge genomic research. In addition to full-service sequencing, we offer hands-on wet-lab training courses and educational seminars to empower users with practical experience.
For more info, contact:
Kaitlyn Williams
Director
Email
Bioinformatics and Statistics Core
The Statistics and Bioinformatics Core provides comprehensive computational genomics and statistical analysis services spanning single-cell and bulk transcriptomics, genetic variant analysis, epigenetics, microbiome analysis, population genetics, and network-based modeling. We offer expertise in GWAS and TWAS, along with rigorous statistical consultation to support robust experimental design from project inception through interpretation. Our dedicated high-performance computing environment features both CPU and heterogeneous GPU architectures, including NVIDIA and AMD GPUs, paired with petabyte-scale, high-throughput storage to support data-intensive workflows. We emphasize reproducible, end-to-end pipelines that ensure scalability, transparency, and long-term usability of results.
For more info, contact:
Dr. Vijay Shankar
Director
Email
South Carolina Translational Research Improving Musculoskeletal Health (SC TRIMH) (COBRE): Multiscale Computational Modeling Core and Advanced Fabrication and Testing Core, Clemson University, Clemson, SC
SC TRIMH’s primary mission is to develop a new generation of NIH-funded investigators by providing the intellectual expertise needed for one-on-one and group mentoring opportunities to early-stage and/or new investigators, financial support for investigators to obtain preliminary data and research infrastructure, through dedicated scientific cores, necessary for investigators to be successful in competing for NIH research awards. The specific aims are to:
Expand the critical mass of funded investigators conducting musculoskeletal research
Strengthen innovative scientific cores that support and advance musculoskeletal research
Advance the ongoing development of an independent, sustainable, multidisciplinary thematic program.
Representative:
Thomas Gallien
Program Manager
Email
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