SC INBRE Announces 2019 Project Program Grant Recipients

South Carolina IDeA Networks of Biomedical Research Excellence (SC INBRE) is pleased to announce our 2019 Bioinformatics Pilot Project Program (BIPP) and Developmental Research Project Program (DRP) grant recipients. We received double the applications this year for both programs and it was a tight competition.

The goal of the SC INBRE Bioinformatics Pilot Project Program is to stimulate interest in the application of genomics and bioinformatics methods by supporting research and student training throughout the SC INBRE and South Carolina Clinical and Translational Research Institute (SCTR) networks. Applications were accepted from institutions of higher education in the SC INBRE network; affiliated members of SCTR; and interested students and faculty at primarily undergrad institutions (PUI) across South Carolina. Projects are to be implemented by faculty and student teams, with a faculty member as PI and all other personnel as co-Investigators. Each project awards up to $10,000 for one-year.

The 2019 BIPP Program recipients are:

Jennifer Grier (with Steven Fiester)


Transcriptomics of Acinetobacter baumannii and its human host by dual RNA-seq

Nathan Hancock

USC Aiken

Genomic Analysis of an RNA Silencing Mutant

Doug Pittman

UofSC Pharmacy

Mutational Signatures Following Thiopurine Treatment in Homologous Recombination Defective Cells

Mark Sarzynski

UofSC Public Health

miRNA bioinformatics of peak VO2 response to exercise training in heart failure USC

The SC INBRE Developmental Research Project Program (DRP) was designed to promote the career development of faculty within the SC INBRE network. DRP proposals focus on Biomedical Science and fit within the broad scientific focus areas of SC INBRE: Regenerative Medicine; Cell and Molecular Biology; Neuroscience; and Bioinformatics.

DRP awards support independent research and mentored career development of each recipient. SC INBRE DRP faculty will utilize SC INBRE support to establish their independent research programs and, in the process, provide research training to students and/or postdoctoral fellows in the Biomedical Sciences. Each project awards up to $50,000 for one year. If SC INBRE’s renewal application is approved and funded by NIH NIGMS, recipients will be eligible to apply for two years of support.

The 2019 DRP Program recipients are:

Brian Booth

Clemson University

Investigation of biochemicals involved in cancer cell redirection

Sri Chandrasekaran

Furman University

Effects of antioxidants of fluconazole resistance in Cryptococcus neoformans

April DeLaurier

USC Aiken

Genetic mechanisms underlying craniofacial skeletal development in zebrafish

Michael Giuliano

College of Charleston

Piece-wise NMR Study of Human Neuropeptides and Their Receptors

Jessica Larsen

Clemson University

Towards Theranostic Technology: Elucidation of Neural Enzyme Upregulation

Holly LaVoie


Pregnancy, TIMP4 and cardiac remodeling

Chang Liu

UofSC Biomedical Engineering

A Nanopore Biosensor for Rapid Detection of Human Immunodeficiency Virus Biomarkers

Moshe Rhodes

College of Charleston

Interactions between the obesogenic compound DOSS and the mouse gut microbiome

Austin Shull

Presbyterian College

An Epigenetic Predisposition Toward Inflammation in Breast Cancer Stem Cells

Chris Varnon RENEWAL

Converse College

Cockroach Model of Alcoholism

Yongren Wu


Estrogen Effect on the Integrity of Ligament-Bone Junction in Thumb Basal Joint